Cambridge, MA based Emulate, Inc. was spun out of the Wyss Institute for Biologically Inspired Engineering at Harvard University (Wyss Institute) in late 2013 to commercialize IP initially developed over five years a $37 MM multiyear DARPA grant, then further de-risked and incubated for three years at the Wyss Institute with $7MM in development funding from the private sector, including a subsidiary of Johnson & Johnson (J&J). Emulate makes transparent chips the size of a USB thumb drive that simulate actual human organs, “Organs-on-Chip”. These chips incorporate actual living human tissue, allowing for greater understanding of how diseases, medicines, chemicals, and foods affect human health.
Organs-on-Chips accurately recreate human biology by reconstructing the microenvironments that cells experience inside the human body. This happens within small fluidic channels that are lined with living human cells. The Organs-on-Chips are made from transparent polymers, which are manufactured using innovative micro engineering methods. Each Organ-on-Chip houses tens of thousands of cells.
Emulate’s Organ-on-Chips are designed to represent the smallest functional unit of the corresponding organ. The chip’s fluid channels allow them to reproduce the body’s blood flow; its flexibility allows them to make a Lung-on-Chip breathe for example. With the chip being transparent a researcher can watch and study the organ functions happen in real-time and with high-fidelity.
For more information on Emulate visit their website at http://emulatebio.com/.